Claude Sonnet 4.5 vs Qwen2.5 72B Instruct
Claude Sonnet 4.5 leads Qwen2.5 72B Instruct on the Artificial Analysis Intelligence Index, 20.7 to 7.7, and Qwen2.5 72B Instruct costs 37.5x less per output token ($0.40 vs $15.00 per million). Updated October 22, 2026; 36 benchmarks have a result for both.
Claude Sonnet 4.5 or Qwen2.5 72B Instruct: which to pick
Only Claude Sonnet 4.5 has a coding score, 39.5 on the Vibe Coding Index; Qwen2.5 72B Instruct has none, so the two cannot be ranked on coding.
Pick Qwen2.5 72B Instruct for output tokens 37.5x cheaper ($0.40 vs $15.00 per million).
- Shared results
- 36
- Claude Sonnet 4.5 only
- 59
- Qwen2.5 72B Instruct only
- 17
- Like-for-like categories
- 7 of 9
Only benchmarks that tested both models count toward a pick; a result only one model has is shown but not compared.
Which one for your work
Each card is decided by one number both models carry. Where only one has it, the card says so and makes no call.
Coding
Vibe Coding Index, six public coding benchmarks
No call
Only Claude Sonnet 4.5 has a coding score, so no call is made.
One side not measured
Intelligence
AA Intelligence Index
Claude Sonnet 4.5
Claude Sonnet 4.5 leads, 20.7 against 7.7.
Same board, both measured
Agentic work
AA Agentic Index
No call
Only Claude Sonnet 4.5 has a AA Agentic Index result, 15.8.
Directional only
Reasoning
GPQA Diamond
No call
Only Claude Sonnet 4.5 has a GPQA Diamond result, 81.6%.
Directional only
Math
AIME
No call
Only Claude Sonnet 4.5 has a AIME result, 88.2%.
Directional only
Knowledge
MMLU Pro
No call
Only Claude Sonnet 4.5 has a MMLU Pro result, 87.4%.
Directional only
Web design
Design Arena: websites
No call
Only Claude Sonnet 4.5 has a Design Arena: websites result, 1189.
Directional only
Long documents
Listed context window
Claude Sonnet 4.5
Claude Sonnet 4.5 takes 1M tokens against 33K.
Listed by OpenRouter
Everyday cost
1K input + 500 output tokens
Qwen2.5 72B Instruct
Claude Sonnet 4.5 $0.011, Qwen2.5 72B Instruct $0.0006 per turn.
List prices
Cost per solved task
One SWE-bench Verified task, solved
No call
Only Claude Sonnet 4.5 has the number, $1.16.
Directional only
At a glance
- Coding index
- Claude Sonnet 4.5 39.5 from 3 benchmarks, Qwen2.5 72B Instruct not benchmarked.
- Widest category
- Math, 40.1 points apart on average over 4 shared benchmarks.
- Widest single gap
- OTIS Mock AIME: Claude Sonnet 4.5 77.8% against Qwen2.5 72B Instruct 8.1%, 69.7 points apart on a 0 to 100 scale.
- Output price
- Claude Sonnet 4.5 $15.00 against Qwen2.5 72B Instruct $0.40 per million output tokens, 37.5x apart.
- Context window
- Claude Sonnet 4.5 takes 1M tokens, Qwen2.5 72B Instruct 33K.
Benchmark by benchmark
First the score: boards each model leads, per category, where both have a result. Then every board, a category to a fold; bars are each result on a 0 to 100 scale, so compare the two in a row, not one row with another.
| Category | Claude Sonnet 4.5 | Bars | Qwen2.5 72B Instruct | Ties |
|---|---|---|---|---|
| Coding | 3 | 0 | ||
| Intelligence | 2 | 0 | ||
| Agentic work | 1 | 0 | ||
| Reasoning | 4 | 0 | ||
| Math | 4 | 0 | ||
| Knowledge | 4 | 0 | ||
| General | 18 | 0 | ||
| All shared boards | 36 | 0 |
CodingLike-for-likeSix of these boards feed the Vibe Coding Index30
| Benchmark | Claude Sonnet 4.5 | Qwen2.5 72B Instruct | Leader |
|---|---|---|---|
| SWE-bench Verified | 74.8% | Not measured | Only Claude Sonnet 4.5 measured |
| SWE-bench Multilingual | 67.0% | Not measured | Only Claude Sonnet 4.5 measured |
| LMArena WebDev | 1394 | Not measured | Only Claude Sonnet 4.5 measured |
| AA Coding Index | 52.1 | Not measured | Only Claude Sonnet 4.5 measured |
| LiveCodeBench (Vals AI) | 73.0% | Not measured | Only Claude Sonnet 4.5 measured |
| SWE-bench Verified (Vals AI) | 70.0% | Not measured | Only Claude Sonnet 4.5 measured |
| Vibe Code Bench (Vals AI) | 22.6% | Not measured | Only Claude Sonnet 4.5 measured |
| LiveCodeBench (Artificial Analysis run) | Not measured | 27.6% | Only Qwen2.5 72B Instruct measured |
| Terminal-Bench Hard (Artificial Analysis run) | Not measured | 4.5% | Only Qwen2.5 72B Instruct measured |
| Terminal-Bench | 46.5% | Not measured | Only Claude Sonnet 4.5 measured |
| GSO-Bench | 14.7% | Not measured | Only Claude Sonnet 4.5 measured |
| WeirdML | 47.7% | 16.0% | Claude Sonnet 4.5 |
| Cybench | 60.0% | Not measured | Only Claude Sonnet 4.5 measured |
| LMArena Text: coding | 1488 | 1292 | Claude Sonnet 4.5 |
| LMArena Text: software and IT | 1473 | 1292 | Claude Sonnet 4.5 |
| LMArena WebDev: React | 1386 | Not measured | Only Claude Sonnet 4.5 measured |
| LMArena WebDev: HTML | 1399 | Not measured | Only Claude Sonnet 4.5 measured |
| Neither model has a result on the other 22 boards here | |||
IntelligenceLike-for-likePublic boards, shown as published, kept out of the index20
| Benchmark | Claude Sonnet 4.5 | Qwen2.5 72B Instruct | Leader |
|---|---|---|---|
| AA Intelligence Index | 20.7 | 7.7 | Claude Sonnet 4.5 |
| Epoch Capabilities Index | 146.7 | 129.0 | Claude Sonnet 4.5 |
Agentic workLike-for-likePublic boards, shown as published, kept out of the index10
| Benchmark | Claude Sonnet 4.5 | Qwen2.5 72B Instruct | Leader |
|---|---|---|---|
| AA Agentic Index | 15.8 | Not measured | Only Claude Sonnet 4.5 measured |
| Design Arena: agents building web apps | 1060 | Not measured | Only Claude Sonnet 4.5 measured |
| Design Arena: agents building full-stack apps | 1050 | Not measured | Only Claude Sonnet 4.5 measured |
| Design Arena: agents building mobile apps | 1137 | Not measured | Only Claude Sonnet 4.5 measured |
| τ²-Bench Telecom | Not measured | 34.5% | Only Qwen2.5 72B Instruct measured |
| METR time horizons | 67.4% | 35.8% | Claude Sonnet 4.5 |
| Remote Labor Index | 2.1% | Not measured | Only Claude Sonnet 4.5 measured |
| GDPval | 42.5% | Not measured | Only Claude Sonnet 4.5 measured |
| BALROG | Not measured | 16.2% | Only Qwen2.5 72B Instruct measured |
| DeepResearch Bench | 52.6% | Not measured | Only Claude Sonnet 4.5 measured |
| TheAgentCompany | Not measured | 5.7% | Only Qwen2.5 72B Instruct measured |
| OSWorld | 62.9% | Not measured | Only Claude Sonnet 4.5 measured |
| Vending-Bench 2 | $3,839 | Not measured | Only Claude Sonnet 4.5 measured |
| Berkeley Function Calling Leaderboard (BFCL) | 73.2% | Not measured | Only Claude Sonnet 4.5 measured |
| Neither model has a result on the other 27 boards here | |||
ReasoningLike-for-likePublic boards, shown as published, kept out of the index40
| Benchmark | Claude Sonnet 4.5 | Qwen2.5 72B Instruct | Leader |
|---|---|---|---|
| GPQA Diamond | 81.6% | Not measured | Only Claude Sonnet 4.5 measured |
| MMMU Pro (Vals AI) | 79.3% | Not measured | Only Claude Sonnet 4.5 measured |
| GPQA Diamond (Artificial Analysis run) | Not measured | 49.1% | Only Qwen2.5 72B Instruct measured |
| Humanity's Last Exam (Artificial Analysis run) | Not measured | 3.6% | Only Qwen2.5 72B Instruct measured |
| GPQA Diamond (Epoch AI run) | 82.3% | 49.1% | Claude Sonnet 4.5 |
| ARC-AGI | 63.7% | Not measured | Only Claude Sonnet 4.5 measured |
| ARC-AGI-2 | 13.6% | Not measured | Only Claude Sonnet 4.5 measured |
| SimpleBench | 54.3% | Not measured | Only Claude Sonnet 4.5 measured |
| Chess puzzles | 10.0% | Not measured | Only Claude Sonnet 4.5 measured |
| Mystery game puzzles | 17.0% | Not measured | Only Claude Sonnet 4.5 measured |
| EBR-bench | 2.4% | Not measured | Only Claude Sonnet 4.5 measured |
| VPCT | 39.8% | Not measured | Only Claude Sonnet 4.5 measured |
| BIG-Bench Hard | Not measured | 79.8% | Only Qwen2.5 72B Instruct measured |
| LMArena Text: hard prompts | 1462 | 1271 | Claude Sonnet 4.5 |
| LMArena Text: expert | 1483 | 1245 | Claude Sonnet 4.5 |
| LMArena Text: hard prompts in English | 1471 | 1279 | Claude Sonnet 4.5 |
| Kagi LLM Benchmark | 57.9% | Not measured | Only Claude Sonnet 4.5 measured |
| Neither model has a result on the other 5 boards here | |||
MathLike-for-likePublic boards, shown as published, kept out of the index40
| Benchmark | Claude Sonnet 4.5 | Qwen2.5 72B Instruct | Leader |
|---|---|---|---|
| AIME | 88.2% | Not measured | Only Claude Sonnet 4.5 measured |
| MGSM (Vals AI) | 94.3% | Not measured | Only Claude Sonnet 4.5 measured |
| AA Math Index | Not measured | 14.0 | Only Qwen2.5 72B Instruct measured |
| AIME 2025 (Artificial Analysis run) | Not measured | 14.0% | Only Qwen2.5 72B Instruct measured |
| OTIS Mock AIME | 77.8% | 8.1% | Claude Sonnet 4.5 |
| FrontierMath, tiers 1 to 3 | 23.9% | Not measured | Only Claude Sonnet 4.5 measured |
| FrontierMath, tier 4 | 2.4% | Not measured | Only Claude Sonnet 4.5 measured |
| ProofBench | 19.0% | Not measured | Only Claude Sonnet 4.5 measured |
| MATH level 5 | 97.7% | 63.2% | Claude Sonnet 4.5 |
| LMArena Text: math | 1449 | 1283 | Claude Sonnet 4.5 |
| LMArena Text: mathematical work | 1462 | 1290 | Claude Sonnet 4.5 |
| Neither model has a result on the other 2 boards here | |||
KnowledgeLike-for-likePublic boards, shown as published, kept out of the index40
| Benchmark | Claude Sonnet 4.5 | Qwen2.5 72B Instruct | Leader |
|---|---|---|---|
| MMLU Pro | 87.4% | Not measured | Only Claude Sonnet 4.5 measured |
| LegalBench (Vals AI) | 84.1% | Not measured | Only Claude Sonnet 4.5 measured |
| CaseLaw (Vals AI) | 62.2% | Not measured | Only Claude Sonnet 4.5 measured |
| CorpFin (Vals AI) | 62.0% | Not measured | Only Claude Sonnet 4.5 measured |
| TaxEval (Vals AI) | 73.3% | Not measured | Only Claude Sonnet 4.5 measured |
| MortgageTax (Vals AI) | 64.0% | Not measured | Only Claude Sonnet 4.5 measured |
| MedQA (Vals AI) | 94.7% | Not measured | Only Claude Sonnet 4.5 measured |
| MedCode (Vals AI) | 44.1% | Not measured | Only Claude Sonnet 4.5 measured |
| MMLU Pro (Artificial Analysis run) | Not measured | 72.0% | Only Qwen2.5 72B Instruct measured |
| SimpleQA Verified | 30.7% | Not measured | Only Claude Sonnet 4.5 measured |
| MMLU | Not measured | 85.3% | Only Qwen2.5 72B Instruct measured |
| AI2 Reasoning Challenge | Not measured | 94.5% | Only Qwen2.5 72B Instruct measured |
| LMArena Text: science | 1448 | 1275 | Claude Sonnet 4.5 |
| LMArena Text: medicine and healthcare | 1444 | 1258 | Claude Sonnet 4.5 |
| LMArena Text: legal and government | 1451 | 1288 | Claude Sonnet 4.5 |
| LMArena Text: business and finance | 1440 | 1253 | Claude Sonnet 4.5 |
| FACTS Benchmark Suite | 40.6% | Not measured | Only Claude Sonnet 4.5 measured |
| Neither model has a result on the other 1 board here | |||
Web designDirectional onlyPublic boards, shown as published, kept out of the index8 boards, none shared
| Benchmark | Claude Sonnet 4.5 | Qwen2.5 72B Instruct | Leader |
|---|---|---|---|
| Design Arena: websites | 1189 | Not measured | Only Claude Sonnet 4.5 measured |
| Design Arena: UI components | 1170 | Not measured | Only Claude Sonnet 4.5 measured |
| Design Arena: game dev | 1166 | Not measured | Only Claude Sonnet 4.5 measured |
| Design Arena: data viz | 1167 | Not measured | Only Claude Sonnet 4.5 measured |
| Design Arena: 3D | 1157 | Not measured | Only Claude Sonnet 4.5 measured |
| Design Arena: all code categories | 1182 | Not measured | Only Claude Sonnet 4.5 measured |
| Design Arena: SVG | 1115 | Not measured | Only Claude Sonnet 4.5 measured |
| Design Arena: ASCII art | 1205 | Not measured | Only Claude Sonnet 4.5 measured |
| Neither model has a result on the other 1 board here | |||
GeneralLike-for-likePublic boards, shown as published, kept out of the index180
| Benchmark | Claude Sonnet 4.5 | Qwen2.5 72B Instruct | Leader |
|---|---|---|---|
| SAGE (Vals AI) | 36.1% | Not measured | Only Claude Sonnet 4.5 measured |
| MedScribe (Vals AI) | 84.5% | Not measured | Only Claude Sonnet 4.5 measured |
| IFBench | Not measured | 36.9% | Only Qwen2.5 72B Instruct measured |
| DTBench | 83.2% | 62.9% | Claude Sonnet 4.5 |
| LMCA | 38.8% | 13.4% | Claude Sonnet 4.5 |
| HellaSwag | Not measured | 84.8% | Only Qwen2.5 72B Instruct measured |
| WinoGrande | Not measured | 82.3% | Only Qwen2.5 72B Instruct measured |
| PIQA | Not measured | 82.6% | Only Qwen2.5 72B Instruct measured |
| LMArena Text | 1438 | 1269 | Claude Sonnet 4.5 |
| LMArena Text: instruction following | 1459 | 1254 | Claude Sonnet 4.5 |
| LMArena Text: creative writing | 1442 | 1221 | Claude Sonnet 4.5 |
| LMArena Text: English | 1450 | 1283 | Claude Sonnet 4.5 |
| LMArena Text: non-English | 1425 | 1252 | Claude Sonnet 4.5 |
| LMArena Text: Chinese | 1460 | 1273 | Claude Sonnet 4.5 |
| LMArena Text: German | 1427 | 1234 | Claude Sonnet 4.5 |
| LMArena Text: Japanese | 1390 | 1180 | Claude Sonnet 4.5 |
| LMArena Text: Korean | 1402 | 1188 | Claude Sonnet 4.5 |
| LMArena Text: French | 1459 | 1280 | Claude Sonnet 4.5 |
| LMArena Text: Spanish | 1458 | 1255 | Claude Sonnet 4.5 |
| LMArena Text: Russian | 1437 | 1264 | Claude Sonnet 4.5 |
| LMArena Text: Polish | 1423 | Not measured | Only Claude Sonnet 4.5 measured |
| LMArena Text: multi-turn | 1465 | 1272 | Claude Sonnet 4.5 |
| LMArena Text: longer queries | 1475 | 1281 | Claude Sonnet 4.5 |
| LMArena Text: writing and language | 1442 | 1247 | Claude Sonnet 4.5 |
| LMArena Text: entertainment and media | 1428 | 1211 | Claude Sonnet 4.5 |
| LMArena Document | 1450 | Not measured | Only Claude Sonnet 4.5 measured |
| Neither model has a result on the other 20 boards here | |||
Image generationNot comparablePublic boards, shown as published, kept out of the index0 boards, none shared
| Benchmark | Claude Sonnet 4.5 | Qwen2.5 72B Instruct | Leader |
|---|---|---|---|
| Neither model has a result on 5 boards here | |||
What each workload costs
Three fixed token mixes at each model's listed price, so per-token rates become a bill.
Chat turn
1K input + 500 output tokens
Qwen2.5 72B Instruct costs less
Repository review
50K input + 3K output tokens
Qwen2.5 72B Instruct costs less
Agent loop
200K input + 10K output tokens
Qwen2.5 72B Instruct costs less
Listed OpenRouter rates, without cache or batch discounts. A workload that does not fit a model's context window would need splitting.
Specification differences
The leading value in a row is marked; a row with a missing value names no leader. Our two rows are marked in red.
| Specification | Anthropic Claude Sonnet 4.5 | Qwen2.5 72B Instruct |
|---|---|---|
| Maker | Anthropic | Qwen |
| Weights | No public weights listed | Open weights |
| Released | September 29, 2025 | September 19, 2024 |
| Context window | 1M | 33K |
| Input $/Mtok | $3.00 | $0.36 |
| Output $/Mtok | $15.00 | $0.40 |
| Coding index | 39.5 | Not benchmarked |
| Independent measurements behind it | 3 | 0 |
| Cost per solved task | $1.16 | Not computable |
| Source | OpenRouter listing | OpenRouter listing |
Questions
Is Claude Sonnet 4.5 better than Qwen2.5 72B Instruct for coding?
Only Claude Sonnet 4.5 has a coding score, 39.5 on the Vibe Coding Index; Qwen2.5 72B Instruct has none, so the two cannot be ranked on coding. Pick Qwen2.5 72B Instruct for output tokens 37.5x cheaper ($0.40 vs $15.00 per million).
Which is cheaper, Claude Sonnet 4.5 or Qwen2.5 72B Instruct?
Claude Sonnet 4.5 costs $3.00 per million input tokens and $15.00 per million output tokens; Qwen2.5 72B Instruct costs $0.36 and $0.40. Cost per solved task is known for Claude Sonnet 4.5 only.
Which has the bigger context window, Claude Sonnet 4.5 or Qwen2.5 72B Instruct?
Claude Sonnet 4.5, with 1M tokens against 33K.
How many benchmarks is the Claude Sonnet 4.5 vs Qwen2.5 72B Instruct comparison based on?
36 benchmarks have a result for both models as of October 22, 2026. Claude Sonnet 4.5's coding index rests on 3 independent benchmarks and Qwen2.5 72B Instruct's on 0. Where only one model has a result, the page says so instead of naming a winner.