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Mixtral 8x22B Instruct vs o4 Mini

o4 Mini leads Mixtral 8x22B Instruct on the Artificial Analysis Intelligence Index, 16.7 to 5.7, and o4 Mini costs 1.4x less per output token ($4.40 vs $6.00 per million). Updated October 21, 2026; 7 benchmarks have a result for both.

Mixtral 8x22B InstructMistral AI
Coding
No data
Overall
5.7
Output $/M
$6.00
0
o4 MiniOpenAI
Coding
No data
Overall
16.7
Output $/M
$4.40
7
vs boards won of 7 shared

Mixtral 8x22B Instruct or o4 Mini: which to pick

Neither model has a coding score yet, so the two cannot be ranked on coding.

Pick Mixtral 8x22B Instruct for work measured by LiveCodeBench (Artificial Analysis run) or AA Intelligence Index, where it leads.

Shared results
7
Mixtral 8x22B Instruct only
0
o4 Mini only
87
Like-for-like categories
5 of 9

Only benchmarks that tested both models count toward a pick; a result only one model has is shown but not compared.

Which one for your work

Each card is decided by one number both models carry. Where only one has it, the card says so and makes no call.

At a glance

Coding index
Mixtral 8x22B Instruct not benchmarked, o4 Mini not benchmarked.
Widest category
Coding, 71.1 points apart on average over 1 shared benchmark.
Widest single gap
LiveCodeBench (Artificial Analysis run): Mixtral 8x22B Instruct 14.8% against o4 Mini 85.9%, 71.1 points apart on a 0 to 100 scale.
Output price
Mixtral 8x22B Instruct $6.00 against o4 Mini $4.40 per million output tokens, 1.4x apart.
Context window
Mixtral 8x22B Instruct takes 66K tokens, o4 Mini 200K.

Benchmark by benchmark

First the score: boards each model leads, per category, where both have a result. Then every board, a category to a fold; bars are each result on a 0 to 100 scale, so compare the two in a row, not one row with another.

Boards won, where both have a result
CategoryMixtral 8x22B InstructBarso4 MiniTies
Coding01
Intelligence02
Reasoning02
Knowledge01
General01
All shared boards07
CodingLike-for-likeSix of these boards feed the Vibe Coding Index01
Coding benchmarks for Mixtral 8x22B Instruct and o4 Mini
BenchmarkMixtral 8x22B Instructo4 MiniLeader
Aider polyglotNot measured72.0%Only o4 Mini measured
SWE-bench VerifiedNot measured64.6%Only o4 Mini measured
SWE-bench MultimodalNot measured33.9%Only o4 Mini measured
LiveCodeBench (Vals AI)Not measured82.2%Only o4 Mini measured
LiveCodeBench (Artificial Analysis run)14.8%85.9%o4 Mini
Terminal-Bench Hard (Artificial Analysis run)Not measured15.2%Only o4 Mini measured
GSO-BenchNot measured3.6%Only o4 Mini measured
WeirdMLNot measured52.6%Only o4 Mini measured
LMArena Text: codingNot measured1368Only o4 Mini measured
LMArena Text: software and ITNot measured1367Only o4 Mini measured
Neither model has a result on the other 28 boards here
IntelligenceLike-for-likePublic boards, shown as published, kept out of the index02
Intelligence benchmarks for Mixtral 8x22B Instruct and o4 Mini
BenchmarkMixtral 8x22B Instructo4 MiniLeader
AA Intelligence Index5.716.7o4 Mini
Epoch Capabilities Index122.0145.5o4 Mini
Agentic workDirectional onlyPublic boards, shown as published, kept out of the index2 boards, none shared
Agentic work benchmarks for Mixtral 8x22B Instruct and o4 Mini
BenchmarkMixtral 8x22B Instructo4 MiniLeader
τ²-Bench TelecomNot measured55.6%Only o4 Mini measured
METR time horizonsNot measured63.9%Only o4 Mini measured
Neither model has a result on the other 37 boards here
ReasoningLike-for-likePublic boards, shown as published, kept out of the index02
Reasoning benchmarks for Mixtral 8x22B Instruct and o4 Mini
BenchmarkMixtral 8x22B Instructo4 MiniLeader
GPQA DiamondNot measured74.5%Only o4 Mini measured
MMMU Pro (Vals AI)Not measured79.7%Only o4 Mini measured
GPQA Diamond (Artificial Analysis run)33.2%78.4%o4 Mini
Humanity's Last Exam (Artificial Analysis run)4.0%16.5%o4 Mini
GPQA Diamond (Epoch AI run)Not measured79.6%Only o4 Mini measured
ARC-AGINot measured58.7%Only o4 Mini measured
ARC-AGI-2Not measured6.1%Only o4 Mini measured
SimpleBenchNot measured38.7%Only o4 Mini measured
Chess puzzlesNot measured22.0%Only o4 Mini measured
Mystery game puzzlesNot measured5.0%Only o4 Mini measured
VPCTNot measured57.5%Only o4 Mini measured
LMArena Text: hard promptsNot measured1351Only o4 Mini measured
LMArena Text: expertNot measured1343Only o4 Mini measured
LMArena Text: hard prompts in EnglishNot measured1366Only o4 Mini measured
LMArena Vision: diagramsNot measured1197Only o4 Mini measured
LMArena Vision: homeworkNot measured1234Only o4 Mini measured
Neither model has a result on the other 5 boards here
MathDirectional onlyPublic boards, shown as published, kept out of the index11 boards, none shared
Math benchmarks for Mixtral 8x22B Instruct and o4 Mini
BenchmarkMixtral 8x22B Instructo4 MiniLeader
AIMENot measured83.7%Only o4 Mini measured
MATH 500 (Vals AI)Not measured94.2%Only o4 Mini measured
MGSM (Vals AI)Not measured93.4%Only o4 Mini measured
AA Math IndexNot measured90.7Only o4 Mini measured
AIME 2025 (Artificial Analysis run)Not measured90.7%Only o4 Mini measured
OTIS Mock AIMENot measured81.7%Only o4 Mini measured
FrontierMath, tiers 1 to 3Not measured36.1%Only o4 Mini measured
FrontierMath, tier 4Not measured4.9%Only o4 Mini measured
MATH level 5Not measured97.8%Only o4 Mini measured
LMArena Text: mathNot measured1389Only o4 Mini measured
LMArena Text: mathematical workNot measured1379Only o4 Mini measured
Neither model has a result on the other 2 boards here
KnowledgeLike-for-likePublic boards, shown as published, kept out of the index01
Knowledge benchmarks for Mixtral 8x22B Instruct and o4 Mini
BenchmarkMixtral 8x22B Instructo4 MiniLeader
MMLU ProNot measured80.6%Only o4 Mini measured
LegalBench (Vals AI)Not measured79.2%Only o4 Mini measured
CorpFin (Vals AI)Not measured59.0%Only o4 Mini measured
TaxEval (Vals AI)Not measured74.8%Only o4 Mini measured
MortgageTax (Vals AI)Not measured64.8%Only o4 Mini measured
MedQA (Vals AI)Not measured96.0%Only o4 Mini measured
MedCode (Vals AI)Not measured33.8%Only o4 Mini measured
MMLU Pro (Artificial Analysis run)53.7%83.2%o4 Mini
SimpleQA VerifiedNot measured19.6%Only o4 Mini measured
GeoBenchNot measured64.0%Only o4 Mini measured
LMArena Text: scienceNot measured1354Only o4 Mini measured
LMArena Text: medicine and healthcareNot measured1361Only o4 Mini measured
LMArena Text: legal and governmentNot measured1350Only o4 Mini measured
LMArena Text: business and financeNot measured1325Only o4 Mini measured
Neither model has a result on the other 3 boards here
Web designDirectional onlyPublic boards, shown as published, kept out of the index6 boards, none shared
Web design benchmarks for Mixtral 8x22B Instruct and o4 Mini
BenchmarkMixtral 8x22B Instructo4 MiniLeader
Design Arena: websitesNot measured985Only o4 Mini measured
Design Arena: UI componentsNot measured983Only o4 Mini measured
Design Arena: game devNot measured1003Only o4 Mini measured
Design Arena: data vizNot measured990Only o4 Mini measured
Design Arena: 3DNot measured854Only o4 Mini measured
Design Arena: all code categoriesNot measured976Only o4 Mini measured
Neither model has a result on the other 3 boards here
GeneralLike-for-likePublic boards, shown as published, kept out of the index01
General benchmarks for Mixtral 8x22B Instruct and o4 Mini
BenchmarkMixtral 8x22B Instructo4 MiniLeader
SAGE (Vals AI)Not measured41.1%Only o4 Mini measured
MedScribe (Vals AI)Not measured69.1%Only o4 Mini measured
IFBenchNot measured68.7%Only o4 Mini measured
Long context reasoning (AA-LCR)Not measured61.0%Only o4 Mini measured
DTBench55.1%77.6%o4 Mini
LMCANot measured26.5%Only o4 Mini measured
Fiction.LiveBenchNot measured77.8%Only o4 Mini measured
Creative writing (Lech Mazur)Not measured75.0%Only o4 Mini measured
LMArena TextNot measured1353Only o4 Mini measured
LMArena Text: instruction followingNot measured1320Only o4 Mini measured
LMArena Text: creative writingNot measured1294Only o4 Mini measured
LMArena VisionNot measured1194Only o4 Mini measured
LMArena Text: EnglishNot measured1367Only o4 Mini measured
LMArena Text: non-EnglishNot measured1337Only o4 Mini measured
LMArena Text: ChineseNot measured1354Only o4 Mini measured
LMArena Text: GermanNot measured1336Only o4 Mini measured
LMArena Text: JapaneseNot measured1308Only o4 Mini measured
LMArena Text: KoreanNot measured1312Only o4 Mini measured
LMArena Text: FrenchNot measured1364Only o4 Mini measured
LMArena Text: SpanishNot measured1346Only o4 Mini measured
LMArena Text: RussianNot measured1334Only o4 Mini measured
LMArena Text: PolishNot measured1358Only o4 Mini measured
LMArena Text: multi-turnNot measured1350Only o4 Mini measured
LMArena Text: longer queriesNot measured1315Only o4 Mini measured
LMArena Text: writing and languageNot measured1316Only o4 Mini measured
LMArena Text: entertainment and mediaNot measured1308Only o4 Mini measured
LMArena Vision: EnglishNot measured1200Only o4 Mini measured
LMArena Vision: ChineseNot measured1218Only o4 Mini measured
LMArena Vision: reading textNot measured1197Only o4 Mini measured
LMArena Vision: humorNot measured1199Only o4 Mini measured
LMArena Vision: captioningNot measured1204Only o4 Mini measured
LMArena Vision: recognizing thingsNot measured1218Only o4 Mini measured
LMArena Vision: creative writingNot measured1166Only o4 Mini measured
Neither model has a result on the other 13 boards here
Image generationNot comparablePublic boards, shown as published, kept out of the index0 boards, none shared
Image generation benchmarks for Mixtral 8x22B Instruct and o4 Mini
BenchmarkMixtral 8x22B Instructo4 MiniLeader
Neither model has a result on 5 boards here

What each workload costs

Three fixed token mixes at each model's listed price, so per-token rates become a bill.

Chat turn

1K input + 500 output tokens

Mixtral 8x22B Instruct$0.0050Fits in one request
o4 Mini$0.0033Fits in one request

o4 Mini costs less

Repository review

50K input + 3K output tokens

Mixtral 8x22B Instruct$0.118Fits in one request
o4 Mini$0.068Fits in one request

o4 Mini costs less

Agent loop

200K input + 10K output tokens

Mixtral 8x22B Instruct$0.460Exceeds the context window
o4 Mini$0.264Exceeds the context window

o4 Mini costs less

Listed OpenRouter rates, without cache or batch discounts. A workload that does not fit a model's context window would need splitting.

Specification differences

The leading value in a row is marked; a row with a missing value names no leader. Our two rows are marked in red.

Specifications of Mixtral 8x22B Instruct and o4 Mini
SpecificationMistral Mixtral 8x22B InstructOpenAI o4 Mini
MakerMistral AIOpenAI
WeightsOpen weightsNo public weights listed
ReleasedApril 17, 2024April 16, 2025
Context window66K200K
Input $/Mtok$2.00$1.10
Output $/Mtok$6.00$4.40
Coding indexNot benchmarkedNot benchmarked
Independent measurements behind it00
Cost per solved taskNot computableNot computable
SourceOpenRouter listingOpenRouter listing

Questions

Is Mixtral 8x22B Instruct better than o4 Mini for coding?

Neither model has a coding score yet, so the two cannot be ranked on coding. Pick Mixtral 8x22B Instruct for work measured by LiveCodeBench (Artificial Analysis run) or AA Intelligence Index, where it leads.

Which is cheaper, Mixtral 8x22B Instruct or o4 Mini?

Mixtral 8x22B Instruct costs $2.00 per million input tokens and $6.00 per million output tokens; o4 Mini costs $1.10 and $4.40. Cost per solved task is known for neither of them.

Which has the bigger context window, Mixtral 8x22B Instruct or o4 Mini?

o4 Mini, with 200K tokens against 66K.

How many benchmarks is the Mixtral 8x22B Instruct vs o4 Mini comparison based on?

7 benchmarks have a result for both models as of October 21, 2026. Mixtral 8x22B Instruct's coding index rests on 0 independent benchmarks and o4 Mini's on 0. Where only one model has a result, the page says so instead of naming a winner.

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