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Mixtral 8x22B Instruct vs Nemotron 3.5 Content Safety

Nemotron 3.5 Content Safety costs 30.0x less per output token than Mixtral 8x22B Instruct ($0.20 vs $6.00 per million). Updated October 22, 2026; no benchmark has tested both models yet.

Mixtral 8x22B InstructMistral AI
Coding
No data
Overall
No data
Output $/M
$6.00
Nemotron 3.5 Content SafetyNVIDIA
Coding
No data
Overall
No data
Output $/M
$0.20
vs $6.00 vs $0.20 per 1M output tokens. Nemotron 3.5 Content Safety is 30.0x cheaper.

Mixtral 8x22B Instruct or Nemotron 3.5 Content Safety: which to pick

Neither model has a coding score yet, so the two cannot be ranked on coding.

Compare them on price, context and the boards below.

No benchmark has tested both yet. Mixtral 8x22B Instruct has results on LiveCodeBench (Artificial Analysis run), SciCode and AA Intelligence Index; Nemotron 3.5 Content Safety has none yet. Compare them on price and context instead.

Which one for your work

Each card is decided by one number both models carry. Where only one has it, the card says so and makes no call.

At a glance

Coding index
Mixtral 8x22B Instruct not benchmarked, Nemotron 3.5 Content Safety not benchmarked.
Widest category
None yet: no category has been tested on both models.
Widest single gap
None yet: no benchmark has tested both models.
Output price
Mixtral 8x22B Instruct $6.00 against Nemotron 3.5 Content Safety $0.20 per million output tokens, 30.0x apart.
Context window
Mixtral 8x22B Instruct takes 66K tokens, Nemotron 3.5 Content Safety 131K.

Benchmark by benchmark

Every board either model has a result on, a category to a fold; bars are each result on a 0 to 100 scale. Only one model is measured on each, so no row names a leader.

CodingDirectional onlySix of these boards feed the Vibe Coding Index2 boards measured
Coding benchmarks for Mixtral 8x22B Instruct and Nemotron 3.5 Content Safety
BenchmarkMixtral 8x22B InstructNemotron 3.5 Content SafetyLeader
LiveCodeBench (Artificial Analysis run)14.8%Not measuredOnly Mixtral 8x22B Instruct measured
SciCode0.0%Not measuredOnly Mixtral 8x22B Instruct measured
Neither model has a result on the other 37 boards here
IntelligenceDirectional onlyPublic boards, shown as published, kept out of the index2 boards measured
Intelligence benchmarks for Mixtral 8x22B Instruct and Nemotron 3.5 Content Safety
BenchmarkMixtral 8x22B InstructNemotron 3.5 Content SafetyLeader
AA Intelligence Index5.7Not measuredOnly Mixtral 8x22B Instruct measured
Epoch Capabilities Index122.0Not measuredOnly Mixtral 8x22B Instruct measured
ReasoningDirectional onlyPublic boards, shown as published, kept out of the index2 boards measured
Reasoning benchmarks for Mixtral 8x22B Instruct and Nemotron 3.5 Content Safety
BenchmarkMixtral 8x22B InstructNemotron 3.5 Content SafetyLeader
GPQA Diamond (Artificial Analysis run)33.2%Not measuredOnly Mixtral 8x22B Instruct measured
Humanity's Last Exam (Artificial Analysis run)4.0%Not measuredOnly Mixtral 8x22B Instruct measured
Neither model has a result on the other 20 boards here
KnowledgeDirectional onlyPublic boards, shown as published, kept out of the index1 board measured
Knowledge benchmarks for Mixtral 8x22B Instruct and Nemotron 3.5 Content Safety
BenchmarkMixtral 8x22B InstructNemotron 3.5 Content SafetyLeader
MMLU Pro (Artificial Analysis run)53.7%Not measuredOnly Mixtral 8x22B Instruct measured
Neither model has a result on the other 17 boards here
GeneralDirectional onlyPublic boards, shown as published, kept out of the index1 board measured
General benchmarks for Mixtral 8x22B Instruct and Nemotron 3.5 Content Safety
BenchmarkMixtral 8x22B InstructNemotron 3.5 Content SafetyLeader
DTBench55.1%Not measuredOnly Mixtral 8x22B Instruct measured
Neither model has a result on the other 45 boards here

What each workload costs

Three fixed token mixes at each model's listed price, so per-token rates become a bill.

Chat turn

1K input + 500 output tokens

Mixtral 8x22B Instruct$0.0050Fits in one request
Nemotron 3.5 Content Safety$0.0003Fits in one request

Nemotron 3.5 Content Safety costs less

Repository review

50K input + 3K output tokens

Mixtral 8x22B Instruct$0.118Fits in one request
Nemotron 3.5 Content Safety$0.011Fits in one request

Nemotron 3.5 Content Safety costs less

Agent loop

200K input + 10K output tokens

Mixtral 8x22B Instruct$0.460Exceeds the context window
Nemotron 3.5 Content Safety$0.042Exceeds the context window

Nemotron 3.5 Content Safety costs less

Listed OpenRouter rates, without cache or batch discounts. A workload that does not fit a model's context window would need splitting.

Specification differences

The leading value in a row is marked; a row with a missing value names no leader. Our two rows are marked in red.

Specifications of Mixtral 8x22B Instruct and Nemotron 3.5 Content Safety
SpecificationMistral Mixtral 8x22B InstructNVIDIA Nemotron 3.5 Content Safety
MakerMistral AINVIDIA
WeightsOpen weightsOpen weights
ReleasedApril 17, 2024June 4, 2026
Context window66K131K
Input $/Mtok$2.00$0.20
Output $/Mtok$6.00$0.20
Coding indexNot benchmarkedNot benchmarked
Independent measurements behind it00
Cost per solved taskNot computableNot computable
SourceOpenRouter listingOpenRouter listing

Questions

Is Mixtral 8x22B Instruct better than Nemotron 3.5 Content Safety for coding?

Neither model has a coding score yet, so the two cannot be ranked on coding. Compare them on price, context and the boards below.

Which is cheaper, Mixtral 8x22B Instruct or Nemotron 3.5 Content Safety?

Mixtral 8x22B Instruct costs $2.00 per million input tokens and $6.00 per million output tokens; Nemotron 3.5 Content Safety costs $0.20 and $0.20. Cost per solved task is known for neither of them.

Which has the bigger context window, Mixtral 8x22B Instruct or Nemotron 3.5 Content Safety?

Nemotron 3.5 Content Safety, with 131K tokens against 66K.

Has any benchmark tested both Mixtral 8x22B Instruct and Nemotron 3.5 Content Safety?

No benchmark has tested both yet. Mixtral 8x22B Instruct has results on LiveCodeBench (Artificial Analysis run), SciCode and AA Intelligence Index; Nemotron 3.5 Content Safety has none yet. Compare them on price and context instead. Data as of October 22, 2026.

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