GPT-4o vs Mixtral 8x22B Instruct
Updated October 21, 2026. 5 benchmarks have a result for both. Coding is ranked on the Vibe Coding Index; every other board is shown as published.
Decision reading
Neither model has a coding score yet, so the two cannot be ranked on coding.
GPT-4o has the edge where the context window is larger, 128K against 66K tokens, and where the benchmark that matters is Humanity's Last Exam (Artificial Analysis run), where it leads.
- Shared results
- 5
- GPT-4o only
- 21
- Mixtral 8x22B Instruct only
- 2
- Like-for-like categories
- 4 of 9
Shared results can support a head-to-head reading. Results only one model has describe coverage, not superiority.
Which one for your work
Each card is decided by one number both models carry. Where only one has it, the card says so and makes no call.
Coding
Vibe Coding Index, six public coding benchmarks
No call
Neither has a coding score yet.
One side not measured
Intelligence
AA Intelligence Index
No call
Only Mixtral 8x22B Instruct has a AA Intelligence Index result, 5.7.
Directional only
Web design
Design Arena: websites
No call
Only GPT-4o has a Design Arena: websites result, 831.
Directional only
Long documents
Listed context window
GPT-4o
GPT-4o takes 128K tokens against 66K.
Listed by OpenRouter
Everyday cost
1K input + 500 output tokens
Mixtral 8x22B Instruct
GPT-4o $0.0075, Mixtral 8x22B Instruct $0.0050 per turn.
List prices
At a glance
- Coding index
- GPT-4o not benchmarked, Mixtral 8x22B Instruct not benchmarked.
- Widest category
- Knowledge, 21.1 points apart on average over 1 shared benchmark.
- Widest single gap
- GPQA Diamond (Artificial Analysis run): GPT-4o 54.3% against Mixtral 8x22B Instruct 33.2%, 21.1 points apart on a 0 to 100 scale.
- Output price
- GPT-4o $10.00 against Mixtral 8x22B Instruct $6.00 per million output tokens, 1.7x apart.
- Context window
- GPT-4o takes 128K tokens, Mixtral 8x22B Instruct 66K.
Benchmark by benchmark
First the score: boards each model leads, per category, where both have a result. Then every board, a category to a fold; bars are each result on a 0 to 100 scale, so compare the two in a row, not one row with another.
| Category | GPT-4o | Bars | Mixtral 8x22B Instruct | Ties |
|---|---|---|---|---|
| Coding | 1 | 0 | ||
| Reasoning | 1 | 1 | ||
| Knowledge | 1 | 0 | ||
| General | 1 | 0 | ||
| All shared boards | 4 | 1 |
CodingLike-for-likeSix of these boards feed the Vibe Coding Index10
| Benchmark | GPT-4o | Mixtral 8x22B Instruct | Leader |
|---|---|---|---|
| SWE-bench Verified | 38.8% | Not measured | Only GPT-4o measured |
| SWE-bench Lite | 38.0% | Not measured | Only GPT-4o measured |
| SWE-bench (full test set) | 18.8% | Not measured | Only GPT-4o measured |
| SWE-bench Multimodal | 30.4% | Not measured | Only GPT-4o measured |
| LiveCodeBench (Artificial Analysis run) | 30.9% | 14.8% | GPT-4o |
| Terminal-Bench Hard (Artificial Analysis run) | 8.3% | Not measured | Only GPT-4o measured |
| Neither model has a result on the other 32 boards here | |||
IntelligenceDirectional onlyPublic boards, shown as published, kept out of the index2 boards, none shared
| Benchmark | GPT-4o | Mixtral 8x22B Instruct | Leader |
|---|---|---|---|
| AA Intelligence Index | Not measured | 5.7 | Only Mixtral 8x22B Instruct measured |
| Epoch Capabilities Index | Not measured | 122.0 | Only Mixtral 8x22B Instruct measured |
Agentic workDirectional onlyPublic boards, shown as published, kept out of the index2 boards, none shared
| Benchmark | GPT-4o | Mixtral 8x22B Instruct | Leader |
|---|---|---|---|
| τ²-Bench Telecom | 25.1% | Not measured | Only GPT-4o measured |
| GDPval | 9.9% | Not measured | Only GPT-4o measured |
| Neither model has a result on the other 37 boards here | |||
ReasoningLike-for-likePublic boards, shown as published, kept out of the index11
| Benchmark | GPT-4o | Mixtral 8x22B Instruct | Leader |
|---|---|---|---|
| GPQA Diamond (Artificial Analysis run) | 54.3% | 33.2% | GPT-4o |
| Humanity's Last Exam (Artificial Analysis run) | 2.4% | 4.0% | Mixtral 8x22B Instruct |
| ARC-AGI | 4.5% | Not measured | Only GPT-4o measured |
| ARC-AGI-2 | 0.0% | Not measured | Only GPT-4o measured |
| Neither model has a result on the other 17 boards here | |||
MathDirectional onlyPublic boards, shown as published, kept out of the index2 boards, none shared
| Benchmark | GPT-4o | Mixtral 8x22B Instruct | Leader |
|---|---|---|---|
| AA Math Index | 6.0 | Not measured | Only GPT-4o measured |
| AIME 2025 (Artificial Analysis run) | 6.0% | Not measured | Only GPT-4o measured |
| Neither model has a result on the other 11 boards here | |||
KnowledgeLike-for-likePublic boards, shown as published, kept out of the index10
| Benchmark | GPT-4o | Mixtral 8x22B Instruct | Leader |
|---|---|---|---|
| MMLU Pro (Artificial Analysis run) | 74.8% | 53.7% | GPT-4o |
| MMLU | 88.1% | Not measured | Only GPT-4o measured |
| Neither model has a result on the other 15 boards here | |||
Web designDirectional onlyPublic boards, shown as published, kept out of the index6 boards, none shared
| Benchmark | GPT-4o | Mixtral 8x22B Instruct | Leader |
|---|---|---|---|
| Design Arena: websites | 831 | Not measured | Only GPT-4o measured |
| Design Arena: UI components | 885 | Not measured | Only GPT-4o measured |
| Design Arena: game dev | 906 | Not measured | Only GPT-4o measured |
| Design Arena: data viz | 858 | Not measured | Only GPT-4o measured |
| Design Arena: 3D | 869 | Not measured | Only GPT-4o measured |
| Design Arena: all code categories | 861 | Not measured | Only GPT-4o measured |
| Neither model has a result on the other 3 boards here | |||
GeneralLike-for-likePublic boards, shown as published, kept out of the index10
| Benchmark | GPT-4o | Mixtral 8x22B Instruct | Leader |
|---|---|---|---|
| IFBench | 34.3% | Not measured | Only GPT-4o measured |
| Long context reasoning (AA-LCR) | 49.3% | Not measured | Only GPT-4o measured |
| DTBench | 64.5% | 55.1% | GPT-4o |
| LMCA | 16.6% | Not measured | Only GPT-4o measured |
| Neither model has a result on the other 42 boards here | |||
Image generationNot comparablePublic boards, shown as published, kept out of the index0 boards, none shared
| Benchmark | GPT-4o | Mixtral 8x22B Instruct | Leader |
|---|---|---|---|
| Neither model has a result on 5 boards here | |||
What each workload costs
Three fixed token mixes at each model's listed price, so per-token rates become a bill.
Chat turn
1K input + 500 output tokens
Mixtral 8x22B Instruct costs less
Repository review
50K input + 3K output tokens
Mixtral 8x22B Instruct costs less
Agent loop
200K input + 10K output tokens
Mixtral 8x22B Instruct costs less
Listed OpenRouter rates, without cache or batch discounts. A workload that does not fit a model's context window would need splitting.
Specification differences
The leading value in a row is marked; a row with a missing value names no leader. Our two rows are marked in red.
| Specification | OpenAI GPT-4o | Mistral Mixtral 8x22B Instruct |
|---|---|---|
| Maker | OpenAI | Mistral AI |
| Weights | No public weights listed | Open weights |
| Released | May 13, 2024 | April 17, 2024 |
| Context window | 128K | 66K |
| Input $/Mtok | $2.50 | $2.00 |
| Output $/Mtok | $10.00 | $6.00 |
| Coding index | Not benchmarked | Not benchmarked |
| Independent measurements behind it | 0 | 0 |
| Cost per solved task | Not computable | Not computable |
| Source | OpenRouter listing | OpenRouter listing |
Questions
Is GPT-4o better than Mixtral 8x22B Instruct for coding?
Neither model has a coding score yet, so the two cannot be ranked on coding. GPT-4o has the edge where the context window is larger, 128K against 66K tokens, and where the benchmark that matters is Humanity's Last Exam (Artificial Analysis run), where it leads.
Which is cheaper, GPT-4o or Mixtral 8x22B Instruct?
GPT-4o costs $2.50 per million input tokens and $10.00 per million output tokens; Mixtral 8x22B Instruct costs $2.00 and $6.00. Cost per solved task is known for neither of them.
Which has the bigger context window, GPT-4o or Mixtral 8x22B Instruct?
GPT-4o, with 128K tokens against 66K.
How many benchmarks is the GPT-4o vs Mixtral 8x22B Instruct comparison based on?
5 benchmarks have a result for both models as of October 21, 2026. GPT-4o's coding index rests on 0 independent benchmarks and Mixtral 8x22B Instruct's on 0. Where only one model has a result, the page says so instead of naming a winner.